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Chemo Therapy Free Cancer Fighting Vaccine Moves To Human Trials

By: Ted Andersen of SFGate

A recent Stanford cancer study that cured 97 percent of mice from tumors has now moved on to soliciting human volunteers for a new cutting-edge medical trial.

The trial is part of a gathering wave of research into immunotherapy, a type of treatment that fights cancer by using the body’s immune system to attack tumors.

“Getting the immune system to fight cancer is one of the most recent developments in cancer,” Dr. Ronald Levy, a Stanford oncology professor who is leading the study, told SFGATE. “People need to know that this is in its early days and we are still looking for safety and looking to make this as good as it can be.”

The treatment is not a true vaccine that creates lasting immunity, but it does feature a vaccine-like injection carrying two immune stimulators that activate the immune system’s T cells to eliminate tumors throughout the body.

Each test subject receives a low dose of radiation plus two rounds of the injected agents, Levy said. No chemotherapy is involved.

The treatment does not work on all types of cancer, Levy said, because each type of cancer has a different set of rules regarding how it can be affected by the immune system.

For the current trials, he is only looking for people with low-grade lymphoma regardless if they have been previously treated. He said Stanford is planning on running two trials by the end of the year with a total of about 35 test subjects.

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